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BMS
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150
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Introduction to the Human Genome
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This course for non-science majors aims to explore our current understanding of the principles of genetics as applied to the human genome. The human genome has been fully sequenced and individuals are now choosing elective surgery based on knowledge of their genetic make-up. Students will be exposed to current ideas of the connection between our genes, health and illnesses and to the similarities and differences in genomes and gene expression among individuals and populations.
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LL
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Lect: 3 hrs.
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| Restriction: Not available to students in the Faculty of Science.
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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280
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Biomedical Science Orientation II
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This course focuses on topics designed to introduce the careers paths available to graduates of the program. It will also review requirements needed to enter many professional schools and opportunities available in non-traditional areas. The lectures will be complemented with speakers who will speak about their educational path and how they arrived at their career. All students in Biomedical Sciences students must enroll in BMS 280 in their third semester of studies.
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Lect: 1 hr.
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GPA Weight: 0.00
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Billing Units: 1
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BMS
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451
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Medical Microbiology
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This course will deal with the study of microorganisms including bacteria, viruses, fungi and parasites which are of medical importance and are capable of causing diseases in human or animals. It includes the laboratory diagnosis of human and animal infections and the role of the laboratory in both the management of infectious diseases and the elucidation of the epidemiology of infections.
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Lect: 3 hrs.
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| Prerequisites: BLG 151
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GPA Weight: 1.00
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Billing Units: 1
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This course will include current aspects of human and molecular genetics including: chromosome structure and function, inheritance of mutations and disease, the human genome and disease gene mapping, cancer genetics, mouse disease models and gene based diagnostics and therapies. It will examine approaches used in genetic screening, genetic counselling and genetic therapy.
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Lect: 3 hrs.
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| Prerequisites: BCH 261, BLG 411, BLG 400
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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605
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Advanced Physiology
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The regulation of physiological processes by hormones and other signalling molecules in chordates will be discussed. An integrated genes-to-environment approach is used to examine aspects of hormonal evolution, physiological information flow, behaviour and neuroendocrinology, and xenobiotic endocrine disruptors.
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Lect: 3 hrs.
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| Prerequisites: BCH 261 and BLG 411 and BLG 600
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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607
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Molecular Genetics and Epigenetics
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A discussion on current aspects of molecular genetics including: chromosome structure and function, inheritance of mutations and disease, the human genome and disease gene mapping. This course will also cover the study of heritable changes in gene expression that occur without a change in DNA sequence, or epigenetics. This course will address the basic principles of epigenetics, the role of epigenetic mechanisms in normal development and human disease with emphasis on the role of chromatin structure.
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Lect: 3 hrs.
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| Prerequisites: BLG 400, BLG 307
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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650
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Experimental Design
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This course will be an advanced discussion of tools and techniques that form the basis for research discovery in genetics, biochemistry and molecular cell biology. Emphasis will be placed in key elements of experimental design including the importance of positive and negative controls, statistical analysis, experimental complementation and understanding limitations. A discussion of bioethical considerations in experimental design will also be included.
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Tut: 2 hrs./Lect: 3 hrs.
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| Prerequisites: BCH 261, BLG 400, BLG 307, BLG 411
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GPA Weight: 1.00
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Billing Units: 1
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This course focuses the integration of complex biological data sets and non-reductionist approaches to studying living organisms. This course will begin by an examination of systems theory, stochasticity in biological systems, emergent behaviors, the advent of high-throughput biological experimental techniques and the use of modeling to understand biological processes. The course will also examine epigenetic systems, lipidomics, metabolomics, synthetic biology, integrative cellular signaling networks and computational modeling of cellular systems. The laboratories will complement the lectures.
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Lect: 3 hrs./Lab: 1.5 hrs.
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| Prerequisites: BLG 411 and BLG 307
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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760
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Critical Thinking in Biomedical Sciences
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The lecture component will emphasize the development and application of strategies and tools to analyse, interpret and critically evaluate knowledge in biomedical sciences through the use of primary literature. Students will learn to recognize outstanding questions, speculative arguments, ambiguities and/or flaws, and logically suggest the use of strategies that might resolve identified issues. The course will also focus on the ability to communicate in written and oral form. Finally, students will learn about and implement bioethical considerations in their arguments. The tutorial component will help students learn to execute critical thinking and communication concepts.
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Tut: 2 hrs./Lect: 3 hrs.
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| Prerequisite: BMS 650
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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770
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Medical Epidemiology
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This course will present an overview of epidemiology - uses, methods, and data sources. It will include an overview of types of human genetic variation, approaches to gene discovery vs. gene characterization. It will also cover the epidemiology behind flu vaccine development and the spread of infectious diseases.
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Lect: 3 hrs.
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| Prerequisite: MTH 380
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GPA Weight: 1.00
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Billing Units: 1
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Molecular aspects of cell cycle regulation in eukaryotic cells from yeast to humans will be covered. This knowledge will be then integrated with current concepts and knowledge about cancer in order to explore the cellular and molecular mechanisms underlying cancer development and progression. Specific topics covered will include the eukaryotic cell cycle, the history of cancer, oncogenes, tumor suppressors, and cancer-causing viruses. The laboratory will complement the lectures and introduce the student to cell culture.
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Lect: 3 hrs./Lab: 1.5 hrs.
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| Prerequisites: BLG 307 and BLG 311 and BLG 411
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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857
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Advanced Immunology
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This course will provide an overview of immunopathology, transplantation, autoimmunity and tumour immunology. It will include an introduction to the genetics and cellular pathogenesis of autoimmune diseases such as type I diabetes and multiple sclerosis. Also included will be the pathogenesis and the treatment of immune-related conditions such as Crohn's Disease and HIV as well as transplantation and graft rejection.
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Lect: 3 hrs.
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| Prerequisite: BLG 856
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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858
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Infection and Immunity
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The primary focus of this course is the interactions between mammalian-specific bacterial, fungal and protozoan pathogens and their hosts. The course will examine molecular mechanisms underlying pathogen-host recognition, pathogen invasion of host cells and hijacking of host cell signalling. The molecular basis of the host immune response to pathogens and how pathogens interact with, modify and/or evade the immune system will also be covered. The course will conclude with a review of appropriate versus inappropriate host immune responses to infectious and non-infectious agents and how these responses contribute to the outcomes of infectious diseases and several infection-related autoimmune.
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Lect: 3 hrs.
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| Prerequisites: BLG 151, BLG 411, BLG 856
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GPA Weight: 1.00
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Billing Units: 1
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BMS
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860
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Stem Cell Biology
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This course will examine the molecular and cell biology of stem cells and their importance in development and maintenance of adult tissues like blood and skin. Additionally, the course will discuss topics such as pluripotency, a discussion and comparison between embryonic and adult stem cells, induced pluripotency and the ethical issues related to stem cell use in medicine.
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Lect: 3 hrs.
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| Prerequisites: BCH 361, BLG 307, BLG 411, BLG 600
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GPA Weight: 1.00
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Billing Units: 1
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An introduction and discussion of the various model organisms employed in the life sciences from the unicellular organisms like E. coli and Baker's yeast to simple and complex multicellular organisms like Drosophila, C. elegans, mouse and Arabidopsis. The course will discuss major discoveries made with these organisms, their advantages and disadvantages and maintain a historical perspective on the use of these organisms.
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Lect: 3 hrs.
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| Prerequisites: BLG 311 and BLG 151 and BLG 400
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GPA Weight: 1.00
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Billing Units: 1
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This course will examine the development, anatomy and function of the nervous systems in various organisms with emphasis on humans and its relationship to behavior and disease. Neuronal structure and function including synapses and neurotransmitters will be discussed. Sensory perception and motor responses will be examined. The current understanding of higher order functions of cognition, learning, memory and communication will be explored.
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Lect: 3 hrs.
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| Prerequisites: BLG 600, BLG 311, BLG 411
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GPA Weight: 1.00
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Billing Units: 1
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